Effect of carotid artery stenting on cognitive function in patients with severe carotid artery stenosis
10.3760/cma.j.issn.1673-4165.2021.07.005
- VernacularTitle:颈动脉支架置入术对重度颈动脉狭窄患者认知功能的影响
- Author:
Bin ZHANG
1
;
Yu JIN
;
Guanqing LI
;
Shukang YU
;
Bing LI
;
Boping XING
Author Information
1. 亳州市人民医院（安徽医科大学附属亳州医院、安徽理工大学附属亳州医院）神经内科三病区 236800
- Keywords:
Carotid stenosis;
Stents;
Cognition;
Neuropsychological tests;
Treatment outcome
- From:
International Journal of Cerebrovascular Diseases
2021;29(7):503-506
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of carotid artery stenting (CAS) on cognitive function in patients with severe carotid artery stenosis.Methods:From January 2019 to December 2020, consecutive patients with severe carotid artery stenosis (stenosis degree ≥70%) treated in the Department of Neurology, Bozhou People's Hospital were selected. According to different treatment schemes, all patients were divided into a CAS group and a control group. The CAS group received CAS combined with the best drug treatment, while the control group only received the best drug treatment. The cognitive function was evaluated by Montreal Cognitive Assessment (MoCA) before treatment and at 6 months after treatment.Results:During the study, 52 patients with severe carotid artery stenosis were enrolled, including 37 patients in the CAS group and 15 in the control group. There were no significant differences in demographic and baseline clinical data between the two groups. All patients in the CAS group completed procedure successfully without any complications. MoCA score in the CAS group was significantly higher than that before treatment ( P<0.001), but not in the control group. There was no significant difference in MoCA score between the patients in the CAS group and the control group before treatment; the MoCA score in the CAS group was significantly higher than that in the control group at 6 months after treatment ( P=0.007). Conclusion:CAS may improve the short-term postoperative cognitive function of patients with severe carotid artery stenosis.
