Regulatory effect of microRNAs on neuroplasticity of ischemic stroke
10.3760/cma.j.issn.1673-4165.2021.05.012
- VernacularTitle:微RNAs对缺血性卒中神经可塑性的调控作用
- Author:
Yongdan CUN
1
;
Pengyue ZHANG
Author Information
1. 云南中医药大学，昆明 650500
- Keywords:
Stroke;
Brain ischemia;
MicroRNAs;
Signal transduction;
Neuronal plasticity
- From:
International Journal of Cerebrovascular Diseases
2021;29(5):382-387
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke is one of the main causes of disability and death. Although intravenous thrombolysis and endovascular mechanical thrombectomy can achieve cerebral vascular recanalization, most patients with ischemic stroke leave serious neurological deficits due to missed treatment window. Neural plasticity is the basis of neural function repair. Recent studies have shown that microRNAs play an indispensable role in regulating neural plasticity. This article reviews the regulatory role of microRNAs on neural plasticity in ischemic stroke, in order to provide reference for the treatment of ischemic stroke.
