Correlation of fluid-attenuation inversion recovery vascular hyperintensity and clinical outcome in patients with middle cerebral artery M1 occlusive stroke
10.3760/cma.j.issn.1673-4165.2021.05.002
- VernacularTitle:大脑中动脉M1段闭塞性卒中患者液体衰减反转恢复序列血管高信号与临床转归的相关性
- Author:
Yan YAN
1
;
Lu LU
;
Shugang CAO
;
Wenting ZHANG
;
Xueyun LIU
;
Xun WANG
;
Mingwu XIA
Author Information
1. 合肥市第二人民医院神经内科 230011
- Keywords:
Stroke;
Brain ischemia;
Infarction, middle cerebral artery;
Arterial occlusive diseases;
Magnetic resonance angiography;
Diffusion magnetic resonance imagi
- From:
International Journal of Cerebrovascular Diseases
2021;29(5):326-330
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation of fluid-attenuation inversion recovery (FLAIR) vascular hyperintensity (FVH) and clinical outcome in patients with middle cerebral artery M1 occlusive stroke.Methods:Patients with acute middle cerebral artery M1 occlusive stroke admitted to the Department of Neurology, the Second Affiliated Hospital of Anhui Medical University from June 2018 to September 2019 were enrolled retrospectively. The demographic and clinical data were collected. Diffusion-weighted imaging (DWI)-Alberta Stroke Program Early CT Score (ASPECTS) and FVH score were performed with MRI images. The modified Rankin Scale (MRS) was used to evaluate the clinical outcome at 90 d after onset. 0-2 was defined as good outcome, and >2 was defined as poor outcome. Multivariate logistic regression analysis was used to determine the independent correlation between FVH and the outcome. Results:A total of 65 patients with acute middle cerebral artery M1 occlusive stroke were enrolled, including 37 males (56.9%). Their age was 64.35±12.13 years. Twenty-nine patients (44.6%) had a good outcome, and 36 (55.4%) had a poor outcome. There were significant differences in triglyceride ( P=0.037), antihypertensive drug treatment ( P=0.037), baseline National Institutes of Health Stroke Scale (NIHSS) score ( P<0.001), DWI-ASPECTS ( P=0.017) and FVH score ( P<0.001) between the poor outcome group and the good outcome group. Multivariate logistic regression analysis showed that FVH score (odds ratio 6.477, 95% confidence interval 1.570-26.716; P=0.010) and NIHSS score (odds ratio 1.869, 95% confidence interval 1.326-2.635; P<0.001) were significantly independently correlated with the poor outcome. However, there was no significant independent correlation between DWI-ASPECTS and the outcome (odds ratio 0.451, 95% confidence interval 0.068-2.988; P=0.410). Conclusions:FVH score is an independent risk factor for poor outcome in patients with acute middle cerebral artery M1 occlusive stroke.
