The role of interleukin-6 and interleukin-10 in febrile seizures
10.3760/cma.j.issn.1673-4408.2021.11.010
- VernacularTitle:IL-6与IL-10在热性惊厥中的作用研究进展
- Author:
Wenyuan CHEN
1
;
Zhuying PEI
Author Information
1. 山西医科大学附属运城医院儿科 044000
- Keywords:
Febrile seizures;
Interleukin-6;
Interleukin-10;
Serum;
Cerebrospinal fluid;
Gene;
Drugs
- From:
International Journal of Pediatrics
2021;48(11):761-765
- CountryChina
- Language:Chinese
-
Abstract:
Febrile seizure is one of the most common convulsive disease in childhood.Its pathogenesis is not yet clear.Sometimes the patients with febrile seizures may have fever after seizure and some epilepsy syndrome is characterized by febrile convulsions in the early stage, which makes the differential diagnosis particularly important.Studies have shown that cytokines and genes are involved in the pathogenesis of febrile convulsions.There are differences in the levels of interleukin-6 and interleukin-10 between febrile seizure and other diseases, and the underlying mechanism varies.This article discusses the research update on the expression of IL-6 and IL-10 in related fields from serum levels, cerebrospinal fluid levels, gene and therapeutic drug innovation, in order to provide ideas for clinical diagnosis, treatment and prevention.
