Advance in autoimmune diseases related to Turner syndrome
10.3760/cma.j.issn.1673-4408.2021.11.007
- VernacularTitle:特纳综合征相关自身免疫性疾病的研究进展
- Author:
Yonghua CHEN
1
;
Yilin ZHU
;
Ke YUAN
;
Chunlin WANG
Author Information
1. 浙江大学医学院附属第一医院儿科，杭州 310003
- Keywords:
Turner syndrome;
Autoimmune disorders;
X-chromosome
- From:
International Journal of Pediatrics
2021;48(11):750-752
- CountryChina
- Language:Chinese
-
Abstract:
Turner syndrome(TS)results from a sex-chromosomal anomaly characterized by presence of one normal X chromosome and the loss of the second X-chromosome in phenotypic females.The typical clinical manifestations of Turner syndrome are short stature, hypogonadal dysplasia, and special physical characteristics(such as neck web, shield chest, elbow valgus, etc.). And it is related to the risk of autoimmune diseases, such as autoimmune thyroiditis, celiac disease, type 1 diabetes, inflammatory bowel disease, alopecia areata or vitiligo.This review will address the autoimmune disorders associated with TS, their pathophysiologic mechanisms and clinical characteristics.
