Progress in diagnosis and treatment of primary lymphoma of bone

VernacularTitle:原发性骨淋巴瘤的诊疗进展
Author: Danyang WU ¹ ; Ran GAO ; Xiaojing YAN
Author Information

1. 中国医科大学附属第一医院血液科，沈阳　110001
Keywords: Lymphoma; Bone neoplasms; Diagnosis; Treatment outcome
From: Journal of Leukemia & Lymphoma 2021;30(10):634-636
CountryChina
Language:Chinese
Abstract: Primary lymphoma of bone (PLB) is a rare extra nodal lymphoma, which accounts for 3%-7% of malignant bone tumors, about 5% of extra nodal lymphomas, and 2% of lymphomas in adults. PLB can occur in any age group, but it is more commonly found in middle-aged and elderly people with the average age of onset of 45-60 years old, and it is slightly more common in males than in females. The patients with PLB usually present with pain or swelling of local soft tissue, and the radiological feature is atypical. It must be diagnosed by pathological biopsy. At present, PLB is mainly treated by systemic chemotherapy combined with radiotherapy of the affected bone. This article will review the current progress in the diagnosis and treatment of PLB.