Research progress on approaches for detection of vitamin E in human blood
10.19485/j.cnki.issn2096-5087.2022.01.010
- Author:
CHEN Yingqi
;
XIN Jiarui
;
HUANG Baifen
;
HU Chonggao
;
YANG Lei
- Publication Type:Journal Article
- Keywords:
vitamin E；tocopherol；tocotrienol；detection technique
- From:
Journal of Preventive Medicine
2022;34(1):46-52
- CountryChina
- Language:Chinese
-
Abstract:
There are eight forms of vitamin E in human blood, including α-, β-, γ-, δ-tocopherols and α-, β-, γ-, δ-tocotrienols. As the most abundant and active form of vitamin E, α-tocopherol is widely accepted as a reliable indicator for nutritional assessment of body vitamin E status across the world. Considering that different vitamin E forms have diverse biological activities, separation and detection of different vitamin E forms in human blood facilitates the understanding of the association between vitamin E and diseases. In this review, the advances in sample-pretreatment techniques and detection techniques for vitamin E in human blood were presented. Currently, the sample-pretreatment techniques include solid-phase extraction, liquid-liquid extraction, dispersive liquid-phase microextraction, supported liquid extraction and direct protein precipitation; the detection techniques include automatic biochemical analysis, enzyme-linked immunosorbent assay, gas chromatography, liquid chromatography and ultra-high performance supercritical fluid chromatography mass spectrometry. This review summarizes the characteristics and scope of above-mentioned techniques used for detection of vitamin E in human blood, so as to provide insights into the selection of an appropriate method for inspection technicians.
- Full text:人体血液维生素E检测技术进展.pdf
