Role of microRNAs in the development and progression of nonalcoholic steatohepatitis
10.3969/j.issn.1001-5256.2021.12.048
- VernacularTitle:microRNA在非酒精性脂肪性肝炎发生发展中的作用
- Author:
Xinyu AN
1
;
Lingxi HU
1
;
Jie QIAO
1
;
Rongqi WANG
1
;
Yuemin NAN
1
Author Information
1. Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China
- Publication Type:Reviews
- Keywords:
Nonalcoholic Steatohepatitis;
MicroRNAs;
Pathologic Processes
- From:
Journal of Clinical Hepatology
2021;37(12):2963-2966
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic steatohepatitis (NASH) has become the second leading cause of hepatitis and can further progress to liver fibrosis, liver cirrhosis, and even liver cancer; however, the detailed pathogenesis of NASH remains unclear, and there is still a lack of effective therapeutic drugs. MicroRNAs (miRNAs) are a class of non-coding, post-transcriptionally regulated, and highly conserved small RNAs in the body and play an important role in a variety of liver diseases. This article mainly reviews the role of miRNAs in the development and progression of NASH.
