Changes in hemostasis and clinical significance of coagulation function test in patients with liver cirrhosis
10.3969/j.issn.1001-5256.2021.12.040
- VernacularTitle:肝硬化患者出凝血系统的变化及凝血功能检测的临床意义
- Author:
Shiqi CHAI
1
;
Jinjun CHEN
1
;
Tingting QI
1
Author Information
1. Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis;
Hemorrhage;
Blood Coagulation Factors;
Blood Coagulation Tests
- From:
Journal of Clinical Hepatology
2021;37(12):2928-2931
- CountryChina
- Language:Chinese
-
Abstract:
The liver plays an important role in procoagulant and anticoagulant mechanisms in human body. There are complex changes in hemostasis in patients with liver cirrhosis, with the presence of interaction between the portal venous system and the peripheral system and differences in etiology, and such patients have a dual trend of hemorrhage and thrombosis. At present, there are certain limitations in coagulation function tests commonly used in clinical practice. The primary etiology and results of various coagulation tests should be considered before initiation of anticoagulant therapy for patients with liver cirrhosis, so as to make the best clinical decisions for patients.