Current status of research on elastography combined with serology in the diagnosis of chronic hepatitis B liver fibrosis
10.3969/j.issn.1001-5256.2021.12.037
- VernacularTitle:弹性成像联合血清学诊断慢性乙型肝炎肝纤维化的研究现状
- Author:
Qiao HE
1
,
2
;
Wencong YUAN
1
,
2
;
Haining FAN
1
,
2
;
He XU
1
,
2
;
Bin REN
1
,
2
Author Information
1. Department of Hepatopancreatobiliary Surgery, Qinghai University Affiliated Hospital, Xining 810001, China
2. Qinghai Province Key Laboratory of Hydatid Disease Research, Xining 810001, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis;
Hepatitis B, Chronic;
Elasticity Imaging Techniques;
Biomarkers;
Diagnosis
- From:
Journal of Clinical Hepatology
2021;37(12):2914-2918
- CountryChina
- Language:Chinese
-
Abstract:
Liver biopsy is the gold standard for the diagnosis of liver fibrosis stage in patients with chronic hepatitis B, but it has certain limitations due to its invasiveness. At present, elastography and serological examination have the advantages of convenience, good repeatability, and dynamic testing and are thus widely used in clinical practice. The accuracy of testing has been supported by a large number of studies, and they have been gradually recommended by various guidelines and expert consensus. However, the diagnostic accuracy of the two methods is affected by factors such as inflammation, obesity, ascites, eating, and intercostal space stenosis, and elastography combined with serological examination can greatly improve the accuracy, sensitivity, and specificity of liver fibrosis staging. With reference to related articles in China and globally, this article reviews the problems of the two methods in the staging of chronic hepatitis B liver fibrosis.
