Mechanism and treatment of portal-systemic circulatory imbalance in hepatorenal syndrome
10.3969/j.issn.1001-5256.2021.12.006
- VernacularTitle:肝肾综合征门体循环失衡的机制与治疗
- Author:
Lihong YANG
1
;
Jinhui YANG
1
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China
- Publication Type:Discussions by experts
- Keywords:
Hepatorenal Syndrome;
Portal Hypertension;
Blood Circulatione;
Therapeutics
- From:
Journal of Clinical Hepatology
2021;37(12):2770-2773
- CountryChina
- Language:Chinese
-
Abstract:
Hepatorenal syndrome (HRS) is a serious complication of end-stage liver disease, and its pathogenesis is associated with the systemic hemodynamic changes such as portal hypertension, arterial vasodilation, reduced cardiac output, reduced effective circulating blood volume, and renal artery contraction, as well as portal-systemic circulatory imbalance. For the treatment of HRS at present, vasoactive agents and interventional treatment are used to change systemic hemodynamics and portal-systemic circulatory imbalance, and early intervention can improve the prognosis of patients.