Imaging Findings of Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion in a 4-Year-Old Male: Case Report and Review of Literature.
10.13104/jksmrm.2013.17.1.41
- Author:
Hyun Gi KIM
1
;
Mi Jung LEE
;
Sarah LEE
;
Myung Joon KIM
;
Chang Hee HONG
Author Information
1. Department of Radiology and Research Institute of Radiological Science, Severance Children's Hospital, Yonsei University, College of Medicine, Korea. mjkim@yuhs.ac
- Publication Type:Case Report
- Keywords:
Renal cell carcinoma;
Xp11.2 translocation;
TFE3 gene fusion;
Diffusion-weighted MRI;
Child
- MeSH:
Carcinoma, Renal Cell;
Child;
Diffusion;
Gene Fusion;
Humans;
Kidney;
Magnetic Resonance Imaging;
Male;
Young Adult
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2013;17(1):41-46
- CountryRepublic of Korea
- Language:English
-
Abstract:
We represent a pathologically proven case of a four-year-old male patient with renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion, which is rare but more frequent in children or young adults. Computed tomography showed about 2.5 cm size ill-defined mass in the right kidney. The mass was hyperechoic on ultrasound. Magnetic resonance imaging demonstrated a mass with capsular enhancement and diffusion restriction. We present a case of Xp11.2 renal cell carcinoma and provide review of the literature.
