Perioperative and long-term outcomes of segmentectomy for ground-glass opacity dominant early stage lung cancer: A single-center large-sample retrospective analysis
- VernacularTitle:肺段切除治疗磨玻璃影为主早期肺癌的围术期及远期效果：单中心大样本回顾性研究
- Author:
Zhenyu YANG
1
;
Chengwu LIU
1
;
Jiandong MEI
1
;
Jian ZHOU
1
;
Yunke ZHU
1
;
Feng LIN
1
;
Hu LIAO
1
;
Lin MA
1
;
Zheng LIU
1
;
Chenglin GUO
1
;
Qiang PU
1
;
Lunxu LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Segmentectomy; ground-glass opacity; lung cancer; prognosis; surgery
- From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(12):1420-1426
- CountryChina
- Language:Chinese
- Abstract: Objective To summarize the perioperative and long-term outcomes of ground-glass opacity (GGO) dominant early stage lung cancer patients treated by anatomic segmentectomy. Methods We collected clinical data of 756 patients from Western China Lung Cancer Database, who underwent intentional anatomic segmentectomy [tumor size (T) ≤ 2 cm, GGO ≥ 50%] in the Department of Thoracic Surgery, West China Hospital, Sichuan University from 2009 to 2018. There were 233 males and 523 females at a median age of 53 (25-83) years including 290 (38.4%) patients of simple segmentectomy and 466 (61.6%) patients of complex segmentectomy. All patients were diagnosed as adenocarcinoma, including 338 (44.7%) patients of minimally invasive adenocarcinoma and 418 (55.3%) patients of invasive adenocarcinoma. Results The median operative time was 115 (38-300) min, the median blood loss was 20 (5-800) mL, 58 (7.7%) patients had postoperative complications and the postoperative stay was 4 (2-24) days. The median follow-up period was 43.0 (30.1-167.9) months. Five-year overall survival rate was 99.5% [95%CI (98.8%, 100.0%)], 5-year recurrence-free survival rate was 98.8% [95%CI (97.5%, 100.0%)], and 5-year lung cancer-specific survival rate was 100.0%. Conclusion Anatomic segmentectomy has favorable perioperative outcomes and excellent prognosis in GGO dominant early stage lung cancer patients.
