Changes in Corneal Sensation, Tear Film Stability and Ocular Surface after Advanced Surface Ablation.
10.3341/jkos.2013.54.3.408
- Author:
Byeong Hee LEE
1
;
Eun Joo KIM
;
Jee Hyun KIM
;
Gwang Ja LEE
;
Kyoo Won LEE
;
Young Jeung PARK
Author Information
1. Cheil Eye Hospital, Daegu, Korea. eyepark9@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Advanced surface ablation;
Dry eye;
Impression cytology
- MeSH:
Anesthesia, Local;
Dry Eye Syndromes;
Eye;
Fluorescein;
Goblet Cells;
Humans;
Metaplasia;
Sensation;
Tears
- From:Journal of the Korean Ophthalmological Society
2013;54(3):408-415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the changes in tearfilm, corneal sensation and ocular surface after advanced surface ablation. METHODS: Tearfilm break-up time (BUT), Schirmer test without local anesthesia, fluorescein staining, corneal sensitivity test, ocular surface disease index (OSDI), and conjunctival impression cytology were evaluated in 50 eyes of 25 patients who underwent advanced surface ablation preoperatively and postoperatively at 2 weeks and at 1, 2, 3, and 6 months. Each value was compared to the preoperative value. RESULTS: OSDI diminished by 2 weeks postoperatively, and corneal sensation diminished by 1 month postoperatively (p < 0.05). There were significant decreases in BUT by 2 weeks to 1 month postoperatively as well as decreases in the Schirmer test by 2 to 3 months postoperatively (p < 0.05). Fluorescein staining increased at 2 weeks postoperatively (p < 0.05). Goblet cells decreased substantially by 1 month postoperatively and conjunctival squamous metaplasia increased significantly by 2 months postoperatively (p < 0.05). CONCLUSIONS: Advanced surface ablation may affect tearfilm, corneal sensation and ocular surface up to 3 months postoperatively. Early treatment of dry eye syndrome following advanced surface ablation should strongly be considered.
