A Case of Adult-onset Metachromatic Leukodystrophy with Normal Nerve Conduction Studies.
- Author:
Ji Soo MOON
1
;
Ji Hyun LEE
;
Min Jeong KIM
;
Jong Kook KIM
;
Kwang Soo KIM
;
Bong Goo YOO
Author Information
1. Department of Neurology, Kosin University College of Medicine, Busan, Korea. ybgne@ns.kosinmed.or.kr
- Publication Type:Case Report
- Keywords:
Metachromatic leukodystrophy;
Peripheral polyneuropathy;
Nerve conduction velocities
- MeSH:
Behavioral Symptoms;
Brain;
Cerebroside-Sulfatase;
Demyelinating Diseases;
Dysarthria;
Gait;
Humans;
Leukocytes;
Leukodystrophy, Metachromatic*;
Magnetic Resonance Imaging;
Memory;
Middle Aged;
Neural Conduction*;
Polyneuropathies
- From:Journal of the Korean Neurological Association
2006;24(3):286-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adult-onset metachromatic leukodystrophy (MLD) is very rare with a combination of cognitive and behavioral symptoms and peripheral polyneuropathy. A 47-year-old man was admitted due to memory impairment, gait disturbance, dysarthria and personality changes for a period of 3 years. The arylsulfatase A level in his leukocytes was decreased. A brain MRI showed bilateral symmetrical demyelination but nerve conduction velocities (NCV) were normal. We report a very rare case of adult-onset MLD with normal NCV.
