Textual Research on Ancient Literature of Classical Prescription Kaixinsan and Its Associated Prescription
10.13422/j.cnki.syfjx.20210114
- VernacularTitle:经典名方开心散及类方的古代文献考证
- Author:
Teng-da YI
1
;
Yu-li LI
1
;
Lin-qiang NIU
1
;
Zhi-qiang TAN
1
;
Rui-ling YANG
2
;
Shun-kui GANG
3
;
Zhen-yi YUAN
1
Author Information
1. Hunan University of Chinese Medicine，Changsha 410208，China
2. Bozhou District Hospital of Traditional Chinese Medicine（TCM），Zunyi 563100，China
3. Kunming Municipal Hospital of TCM，Kunming 650500，China
- Publication Type:Research Article
- Keywords:
famous classical formulas;
Kaixinsan;
associated prescriptions;
compound preparation;
textual research
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(5):8-15
- CountryChina
- Language:Chinese
-
Abstract:
The classical prescription Kaixinsan，which is recorded in an ancient medical book named Beiji Qianjin Yaofang，is one of the famous prescriptions used by ancient physicians to treat amnesia. Research on classical prescriptions has attracted more and more attention from scientific research institutions and related enterprises. Based on ancient books，textual research on origins and development of prescriptions，combing the evolution of prescriptions，preparations，oral ways，taboos and others are the important contents of the study on classical prescriptions. The research results show that the creation of Kaixinsan in Beiji Qianjin Yaofang can be traced back to Kaixinsan recorded in Jiyanfang and Dingzhiwan recorded in Gujinluyanfang. Later generations of physicians created many associated prescriptions in the process of applying Kaixinsan，and the efficacy of these prescriptions was constantly expanded with the development of the times. In the Tang and Song dynasties，Kaixinsan and its associated prescriptions were mainly used to treat amnesia，sorrow，fear，and other diseases. In the Jin and Yuan dynasties，these prescriptions were also used to treat convulsions and yawning. In the Ming dynasty， they were mainly for the treatment of hyperopia， myopia， sprematorrhea，and constipation. In the Qing dynasty，these herbs could be used to treat auricular deafness， aging and sweating. The dosage of Ginseng Radix et Rhizoma and Poria should be increased in the treatment of farsightedness，spermatorrhea and blurred urine，and in the treatment of nearsightedness，the dosage of Polygalae Radix and Haliotidis Concha should be increased. The main pathogenesis of the disease that Kaixinsan and its associated prescriptions treated could be summarized as the deficiency of heart and spleen，imbalance between heart-Yang and kidney-Yin，and the internal resistance of phlegm stagnation. By summarizing the contents of the preparation of tradition Chinese medicine products for Kaixinsan and its associated prescriptions，it is suggested that the dosage form of Kaixinsan can be pills，with the specification size confroming to the most record of ancient generations of physicians，as big as Firmiana platanifolia's fruit.The volume of a single pill is about 0.25 mL and the weight is about 0.3 g. The initial dosage is fifteen pills，which can be modified according to the severity of the illness，with no more than forty pills for each time，three times a day. Also，some excitant food like the sour food，sweet food and mutton should be avoided during the medication. The above research results can provide literature basis for the development of compound tradition Chinese Medicine preparation of Kaixinsan.
