Research Progress on Chemical Constituents and Pharmacological Effects of Asari Radix et Rhizoma
10.13422/j.cnki.syfjx.20202353
- VernacularTitle:细辛的化学成分及药理作用研究进展
- Author:
Hao WU
1
;
Xiao-yin WEN
1
;
Peng YAN
1
;
Shui-rong SHEN
2
;
Xiao-dong LIU
1
;
Ke-fang LAI
1
Author Information
1. National Clinical Research Center for Respiratory Disease，State Key Laboratory of Respiratory Disease，Guangzhou Institute of Respiratory Health，The First Affiliated Hospital of Guangzhou Medical University，Guangzhou 510182，China
2. Guangdong Institute of Nanshan Pharmaceutical Innovation， Guangzhou 510530，China
- Publication Type:Research Article
- Keywords:
Asari Radix et Rhizoma;
volatile oil;
non-volatile components;
pharmacological effects;
pharmacodynamic material basis;
anti-inflammatory;
antitussive
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(4):186-195
- CountryChina
- Language:Chinese
-
Abstract:
Asari Radix et Rhizoma （ARR） is a traditional Chinese medicine for relieving exterior syndrome， and its roots and stems contain rich chemical components， including volatile oils （terpenoids， aromatics and aliphatics）， lignans， flavonoids， etc. Clinically， it has been traditionally used for the treatment of diseases such as phlegm and cough， anemofrigid cold， rheumatic arthralgia due to its ability to spread cold. Modern pharmacological studies have shown that ARR played beneficial roles in analgesic， anti-inflammatory， antitussive， antiasthmatic， antiviral， antibacterial， sedative， antioxidative， and antidepressant responses， antihypertension， as well as tumor suppression. The current studies on the chemical composition of ARR mainly focused on volatile components， and little information is available for the occurrence and pharmacological effects of non-volatile components. In addition， there is a lack of clear classification of chemical components and the distribution of chemical components in medicinal parts and the origin of species. Therefore， in this study， the authors reviewed a large number of literature on the chemical compositions and pharmacological effects of ARR， and hoping to provide a reference for further pharmacological research and the new drug development of ARR.
