Potential Impact of Gut Microbiota on Spinal Cord Injury (review)
10.3969/j.issn.1006-9771.2019.12.011
- VernacularTitle:肠道菌群对脊髓损伤潜在影响的研究进展
- Author:
Xiao-hua ZHAO
1
;
Rui-han ZHOU
1
;
Wei GUO
2
;
Ri-zhao PANG
3
;
Wen-chun WANG
3
;
An-ren ZHANG
3
Author Information
1. School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China
2. Pre-treatment Center of Leshan Traditional Chinese Medicine Hospital, Leshan, Sichuan 614000, China
3. Department of Rehabilitation Medicine, the General Hospital of Western Theater Command, Chengdu, Sichuan 610083, China
- Publication Type:Research Article
- Keywords:
spinal cord injury;
gut microbiota;
inflammation;
metabolites;
aryl hydrocarbon receptor;
short-chain fatty acids;
lipopolysaccharides;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2019;25(12):1434-1438
- CountryChina
- Language:Chinese
-
Abstract:
With the deepening of microbial research in central nervous system diseases, the role of gut microbiota in spinal cord injury has also received extensive attention. At present, it is mainly focused on exploring the changes of gut microbiota after spinal cord injury and the potential effects of aryl hydrocarbon receptor agonists, short-chain fatty acids and lipopolysaccharides produced by bacterial metabolism on secondary inflammation after injury, and it is recognized that gut microbiota or supplemental flora metabolites may be a potential pathway for the treatment of spinal cord injury.
