Advance in Aromatase Inhibitor Related Arthralgias (review)
10.3969/j.issn.1006-9771.2019.07.013
- VernacularTitle:芳香化酶抑制剂相关关节痛研究进展
- Author:
Jiu-gen ZHONG
1
;
Xiao-hui HOU
1
;
Hao LAN
2
Author Information
1. School of Kinesiology, Shanghai University of Sport, Shanghai 200438, China
2. Guangzhou Sport University, Guangzhou, Guangdong 510000, China
- Publication Type:Research Article
- Keywords:
breast cancer;
aromatase inhibitors;
arthralgia;
exercise;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2019;25(7):805-812
- CountryChina
- Language:Chinese
-
Abstract:
Estrogen deficiency, inflammatory reactions, metabolic disorders, etc., are considered to be possible mechanisms leading to arthralgias (or joint pain) associated with aromatase inhibitors (AIs) in breast cancer patients. The use of exercise and other non-pharmacological means (such as vitamin D, Omega-3 fatty acids, acupuncture, etc.) may relieve AIs-related arthralgia, and exercise may play a direct or indirect role to deal with the related pathogenesis. But the results of the studies are still controversial.