Advance in Relationship between Obstructive Sleep Apnea and Stroke (review)
10.3969/j.issn.1006-9771.2019.07.008
- VernacularTitle:阻塞性睡眠呼吸暂停与脑卒中相关性的研究进展
- Author:
Jing-mian CHEN
1
;
Zong-jun LI
1
;
Pei-lan LI
1
;
Tong ZHANG
1
Author Information
1. Beijing Bo’ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
- Publication Type:Research Article
- Keywords:
obstructive sleep apnea;
stroke;
epidemiology;
pathophysiology;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2019;25(7):783-787
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA) may increase the risk of stroke, and patients with stroke are also prone to suffer OSA. Advanced age, high body mass index, male, hypertension and diabetes are risk factors for stoke in OSA patients, and severe sleep apnea may also be associated with poor functional outcomes of stroke. Potential pathophysiological mechanisms may include endothelial dysfunction, abnormal neuromodulation, metabolic abnormalities, change of cerebral hemodynamic and hypercoagulability. Continuous positive airway pressure (CPAP) is the standard treatment for patients with moderate to severe OSA, but it has not been proved that CPAP can reduce the risk of cardiovascular events including stroke.
