Application of Functional Near-infrared Spectroscopy in Brain Area Activation Research: Dominant and Non-dominant Hand under Active Grasp-release Task
10.3969/j.issn.1006-9771.2021.09.010
- VernacularTitle:功能性近红外光谱技术在利手、非利手主动抓握-释放任务下脑区激活研究中的应用
- Author:
Chao-jin-zi LI
1
;
Fu-biao HUANG
1
;
Xiao-xia DU
1
;
Hao-jie ZHANG
1
;
Tong ZHANG
1
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
- Publication Type:Research Article
- Keywords:
functional near-infrared spectroscopy;
upper extremity;
motor function;
sensorimotor cortex;
premotor cortex
- From:
Chinese Journal of Rehabilitation Theory and Practice
2021;27(9):1066-1071
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To apply functional near-infrared spectroscopy (fNIRS) to analyze brain activity pattern of bilateral sensorimotor cortex (SMC) and premotor cortex (PMC) during complex dominant and non-dominant hand movement in healthy subjects. Methods:From August to December, 2019, 15 right-handed healthy residents were recruited. The block designed grip-release task was used in the subjects, and detected oxyhemoglobin and deoxyhemoglobin concentration with fNIRS to analyze the activation of bilateral SMC, PMC and prefontal cortex in term of activation channels and intensity. Results:For the oxyhemoglobin concentration, the number of activated channels was the same in both hemispheres during right (dominant) hand movement, and the activation of left SMC was stronger (P < 0.05); however, more channels were activated in the right hemisphere during left (non-dominant) hand movement, and the activation of right SMC was stronger (P < 0.05). For the deoxyhemoglobin concentration, more channels were activated in the contralateral hemisphere during either dominant or non-dominant hand movement, and the activation of left SMC, Channel 12 (left PMC) and Channel 26 (right PMC) were stronger during right (dominant) hand movement (P < 0.05). Conclusion:It is feasible to use fNIRS to study the activation of hand movement related brain regions during complex movement of dominant and non-dominant hand, especially with the results of oxyhemoglobin concentration.
