The effect of fine particulate matter on atherosclerosis and its mechanism
10.19485/j.cnki.issn2096-5087.2021.10.010
- Author:
CHEN Huan
;
LIU Yongsheng
;
YIN Yangguang
- Publication Type:Journal Article
- Keywords:
fine particulate matter；atherosclerosis；cardiovascular disease
- From:
Journal of Preventive Medicine
2021;33(10):1017-1021
- CountryChina
- Language:Chinese
-
Abstract:
Fine particulate matter (PM2.5) not only directly damages lung tissue, but also can be absorbed into blood through alveolar capillaries, which is toxic to the cardiovascular system. PM2.5 can affect lipid metabolism, endothelial function, coagulation and thrombosis through oxidative stress, inflammatory reaction, autonomic nervous dysfunction and immune regulation abnormality, so that it promote arteriosclerosis, plaque instability, and increase the morbidity and mortality of cardiovascular disease. We reviewed the effects and mechanisms of PM2.5 on arteriosclerosis, in order to provide the evidence for the studies into prevention of cardiovascular diseases caused by air pollution.
- Full text:PM2.5对动脉粥样硬化的影响及机制.pdf
