Mechanism of autophagy in the development and progression of autoimmune hepatitis
10.3969/j.issn.1001-5256.2021.11.044
- VernacularTitle:细胞自噬在自身免疫性肝炎发生发展中的作用机制
- Author:
Peiwei YANG
1
;
Guangwei LIU
1
;
Wenxia ZHAO
1
Author Information
1. Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Reviews
- Keywords:
Hepatitis, Autoimmune;
Autophagy;
Immunity, Innate
- From:
Journal of Clinical Hepatology
2021;37(11):2689-2691
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a process of self-defense and self-repair of cells and tissues and plays an important role in regulating the body's immune inflammatory response and maintaining the homeostasis of liver cells. This article summarizes the mechanism of autophagy in the development and progression of autoimmune hepatitis (AIH) from the aspects of the role of autophagy in regulating immune inflammatory response, regulating immune signal transduction, and preventing overactivated innate immune response. It is believed that autophagy may reveal the mechanism of AIH and provide new ideas and methods for the research on AIH.
