Role of angiopoietin-like proteins in the development of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2021.11.042
- VernacularTitle:血管生成素样蛋白在非酒精性脂肪性肝病发展中的作用
- Author:
Peiyu ZHENG
1
;
Xiuqin AN
1
;
Jinchun LIU
2
Author Information
1. Graduate School of Shanxi Medical University, Taiyuan 030001, China
2. Department of Gastroenterology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Angiopoietins;
Ipid Metabolism
- From:
Journal of Clinical Hepatology
2021;37(11):2680-2683
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin-like proteins (ANGPTLs) are a family of secretory glycoproteins recently found to be constitutionally homologous with angiogenin and play a role in the regulation of angiogenesis. In recent years, more and more studies have shown that ANGPTLs play an important role in glucose and lipid metabolism, inflammation, and tumor. As we all know, nonalcoholic fatty liver disease and its disease spectrum are closely associated with metabolism, inflammation, and tumor. This article reviews the role of ANGPTLs in various diseases associated with nonalcoholic fatty liver disease, in order to provide new ideas for the prevention and treatment of nonalcoholic fatty liver disease in clinical practice.
