Effect of diet-gut microbiota axis on nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2021.11.041
- VernacularTitle:饮食-肠道菌群轴对非酒精性脂肪性肝病的影响
- Author:
Shenglan ZENG
1
;
Rongzhen ZHANG
2
;
Na WANG
2
;
Tingshuai WANG
1
;
Liting TAN
1
;
Dewen MAO
2
Author Information
1. The First Clinical Medical College of Guangxi University of Chinese Medicine, Nanning 530023, China
2. Division I of Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Gastrointestinal Microbiome;
Healthy Diet
- From:
Journal of Clinical Hepatology
2021;37(11):2676-2679
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of nonalcoholic fatty liver disease (NAFLD) is increasing. Diet is considered one of the main driving forces regulating the composition of intestinal microbiota, and the intestine and the liver are closely linked through the portal vein, so changes in gut microbiota may affect liver function and promote inflammation, insulin resistance, and steatosis, thereby causing NAFLD. This article elaborates on the relationship between diet, gut microbiota, and the liver and the research advances in how this axis promotes the progression of NAFLD, as well as the change in potential mechanism due to intestinal dysbacteriosis and related treatment methods.
