Impact of nonalcoholic fatty liver disease on intestinal immune cells
10.3969/j.issn.1001-5256.2021.11.039
- VernacularTitle:非酒精性脂肪性肝病对肠道免疫细胞的影响
- Author:
Yalan LEI
1
;
Jian BI
1
;
Jingwei MAO
1
Author Information
1. Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Enterohepatic Circulation;
Macrophages;
Dendritic Cells;
Lymphocytes
- From:
Journal of Clinical Hepatology
2021;37(11):2667-2671
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) interacts with the intestinal immune system due to enterohepatic circulation and immune cell recruitment and recirculation. Intestinal immune imbalance promotes liver inflammation and fibrosis in the process of NAFLD, and meanwhile, NAFLD can cause disorders in the number and function of immune cells in the liver and intestinal tract. This article mainly elaborates on the impact of NAFLD on intestinal immune cells and briefly summarizes the new treatment methods for NAFLD targeting at intestinal immune cells, in order to provide a new understanding of the pathogenesis and treatment of NAFLD.
