Noninvasive diagnostic models for chronic hepatitis B liver fibrosis
10.3969/j.issn.1001-5256.2021.10.034
- VernacularTitle:慢性乙型肝炎肝纤维化的无创诊断模型
- Author:
Qin YANG
1
;
Huaie LIU
1
;
Jing YOU
1
;
Jie DING
2
;
Danyang CHEN
1
Author Information
1. Department of Infectious Diseases, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China
2. Department of Hepatology, The Third People's Hospital of Kunming, Kunming 650032, China
- Publication Type:Reviews
- Keywords:
Hepatitis B, Chronic;
Liver Cirrhosis;
Diagnostic
- From:
Journal of Clinical Hepatology
2021;37(10):2420-2424
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus (HBV) infection is still a public problem that seriously threatens human health. Evaluation of liver fibrosis progression with an efficient noninvasive model is of great significance for condition assessment, disease management, and prognostic evaluation in patients with chronic HBV infection. This article reviews the noninvasive models commonly used in the diagnosis of liver fibrosis in recent years, summarizes the research background, methods, related studies, and advantages and disadvantages of these models, and analyzes the current research status and possible development trends of liver fibrosis assessment models. Recent studies have shown that although current models are not perfect for Chinese patients with chronic HBV infection as the main predisposing factor for liver fibrosis, the excellent performance of noninvasive models in liver fibrosis assessment provides a reference for the assessment of liver fibrosis in patients with chronic HBV infection and can replace liver biopsy to a certain extent.
