Research advances in central nervous system changes in patients with primary biliary cholangitis
10.3969/j.issn.1001-5256.2021.10.003
- VernacularTitle:原发性胆汁性胆管炎患者中枢神经系统改变相关研究进展
- Author:
Yinan HU
1
;
Yulong SHANG
1
;
Xinming ZHOU
1
Author Information
1. Department of Gastroenterology, Xijing Hospital, Air Force Medical University, Xi'an 710032, China
- Publication Type:Discussions by experts
- Keywords:
Liver Cirrhosis;
Cholestasis Cholangitis;
Central Nervous System;
Magnetic Resonance Imaging
- From:
Journal of Clinical Hepatology
2021;37(10):2269-2271
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is an autoimmune liver disease manifesting as cholestasis and is often observed in the middle-aged and elderly women. About 50% of the patients have fatigue and itching, and 20% have depression or mood changes. In recent years, a number of studies have shown that the non-specific symptoms of patients with primary biliary cholangitis (PBC), such as fatigue, itching, and cognitive changes, are associated with the structural and functional changes of the central nervous system. Early identification of preclinical PBC patients through brain imaging changes may be one of the ways for the early diagnosis of this disease.
