Research advances in autophagy-related signal molecules in nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2021.09.044
- VernacularTitle:自噬相关信号分子在非酒精性脂肪性肝病中的作用
- Author:
Jingxia HE
1
;
Xiuqin AN
1
;
Jinchun LIU
2
Author Information
1. Graduate School of Shanxi Medical University, Taiyuan 030001, China
2. Department of Gastroenterology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Autophagy;
Signal Transduction
- From:
Journal of Clinical Hepatology
2021;37(9):2220-2224
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) has become one of the main causes of chronic liver diseases worldwide and is closely associated with metabolic syndrome. In-depth studies on the pathogenesis of NAFLD in recent years have shown that autophagy is a highly conservative process in eukaryotes and plays an important role in the progression of NAFLD, and therefore, it is expected to become a new target for the treatment of NAFLD. This article reviews the research advances in autophagy-related signal molecules in NAFLD, in order to provide new ideas for the treatment of NAFLD.