Research advances in monomers of Chinese herbs in treatment of liver fibrosis by regulating oxidative stress
10.3969/j.issn.1001-5256.2021.09.039
- VernacularTitle:中药单体调控氧化应激抗肝纤维化的机制和价值
- Author:
Zhiwen ZHOU
1
;
Shan LI
2
;
Xianghua LIU
3
;
Ningning LI
4
;
Ning SUN
3
;
Baoping LU
1
Author Information
1. The Second Clinical Medical School, Henan University of Chinese Medicine, Zhengzhou 450046, China
2. School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China
3. Academy of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China
4. Henan Medical College, Zhengzhou 451191, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis;
CHEMICAL PRINCIPLES (TCD);
Oxidative Stress;
Signal Transduction
- From:
Journal of Clinical Hepatology
2021;37(9):2198-2202
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrosis, a common pathological process of most types of chronic liver diseases, is caused by the excessive deposition of extracellular matrix proteins after chronic liver injury. An increasing number of evidence has shown that oxidative stress is closely associated with the development and progression of liver fibrosis and is involved in the pathological process of liver fibrosis caused by various factors. With natural constituents and a clear structure, Chinese herbal monomers herbs have achieved a marked clinical effect in the treatment of liver fibrosis. This article reviews the research advances in monomers of Chinese herbs in the treatment of liver fibrosis by regulating oxidative stress-related signaling pathways.
