Retrospective investigation and analysis of off-label drug use for tic disorder in a tertiary women’s and children’s hospital
10.12206/j.issn.1006-0111.202101023
- VernacularTitle:某三甲妇儿医院抽动障碍超说明书用药回顾性调查分析
- Author:
Aiyun LIN
1
;
Hongtao SONG
2
;
Shan HUANG
2
Author Information
1. Department of Pharmacy, Women’s and Children’s Hospital Affiliated to School of Medicine, Xiamen University, Xiamen 361001, China.
2. Department of Pharmacy, No. 900 Hospital of Joint Logistics Support Force of the PLA, Fuzhou 350025, China.
- Keywords:
tic disorder;
off-label drug use;
drug safety
- From:
Journal of Pharmaceutical Practice
2021;39(6):573-576
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the current situation of off-label drug use for tic disorder in a tertiary maternity and child hospital, so as to promote clinical safe and rational drug use. Methods Through the hospital information system, the pediatric outpatient prescriptions diagnosed with tic disorder from July 2019 to August 2020 were selected, and the prescriptions of off-label use was evaluated according to the 2020 off-label drug management regulations. Results A total 1251 pediatric prescriptions diagnosed with tic disorder were collected. The incidence of off-label drug use was 29.58%. The main types of off-label were over-indications and over-age. The main varieties of off-label drug use were risperidone tablets (47.84%) and aripiprazole tablets (43.74%). Conclusion The off-label use of drug for tic disorder in pediatric outpatient department of our hospital is relatively common，and it is necessary to standardize the management of off-label drug use to ensure rational drug use.
