Recent advances in biomarkers of sepsis
10.12206/j.issn.1006-0111.202105040
- VernacularTitle:脓毒症生物标志物的最新进展
- Author:
Jingxin ZHAO
1
;
Chaoyu MIAO
1
;
Tianying XU
2
,
3
Author Information
1. Department of Pharmacology.
2. Department of Pharmacology
3. Department of Anesthetic Pharmacology, Naval Medical University, Shanghai 200433, China.
- Keywords:
sepsis;
biomarker;
diagnosis;
prognosis
- From:
Journal of Pharmaceutical Practice
2021;39(6):491-498
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis can cause life-threatening organ dysfunction and is one of the leading causes of death in critically ill patients. Early diagnosis and correct treatment of sepsis are the key to reducing the fatality, however, there is no golden standard for diagnosis at present. The ideal sepsis biomarker can be used for early diagnosis and predicting poor prognosis with good sensitivity and specificity. There are many candidate biomarkers for sepsis. This article reviews the latest developments on acute phase proteins, soluble receptors, non-coding RNAs and other candidate biomarkers of sepsis that attracted more recent attention.