Lipid metabolism in atrial fibrillation and its current research status
10.7507/1007-4848.202010001
- VernacularTitle:脂代谢在心房颤动中的研究现状
- Author:
Mengwei LV
1
,
2
;
Tao LI
3
;
Yongjun QIAN
3
;
Yangyang ZHANG
4
Author Information
1. 1. Department of Cardiovascular Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, P.R.China
2. 2. Shanghai East Hospital of Clinical Medical College, Nanjing Medical University, Shanghai, 200120, P.R.China
3. Department of Cardiovascular Surgery, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
4. Department of Cardiovascular Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, P.R.China
- Publication Type:Journal Article
- Keywords:
Atrial fibrillation;
lipid metabolism;
metabolic remodeling;
diagnosis and treatment;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(11):1371-1375
- CountryChina
- Language:Chinese
-
Abstract:
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The metabolic changes of atrial myocytes, especially lipid metabolism, have a significant impact on the electrical signals and structural remodeling of atrial tissue, and play an important role in the occurrence and development of AF. The reduction of fatty acid oxidation ratio and increased aerobic glycolysis ratio are characteristic changes of tissue metabolic remodeling in AF. In this review, we will introduce the latest research status of lipid metabolism in AF from aspects of AF metabolism, clinical treatment and diagnosis and prognosis.
