Localization of small pulmonary nodules with magnetic beads: An animal experiment
- VernacularTitle:磁珠肺小结节定位技术的动物实验研究
- Author:
Lu LV
1
,
2
,
2
,
3
,
3
,
4
;
Aihua SHI
2
,
3
,
5
,
6
;
Xiaopeng YAN
2
,
2
,
3
,
3
,
6
,
7
,
8
;
Zhixuan ZHANG
1
,
2
,
2
,
3
,
3
,
9
;
Guxiang ZHOU
2
,
3
,
10
;
Junke FU
2
,
3
,
11
;
Feng MA
2
,
3
,
6
,
12
;
Haohua WANG
2
,
2
,
3
,
3
,
6
,
7
,
8
;
Yi LV
2
,
2
,
3
,
3
,
6
,
7
,
8
;
Yong ZHANG
1
,
2
,
2
,
3
,
3
,
6
,
13
Author Information
- Publication Type:Journal Article
- Keywords: Magnetic beads; small pulmonary nodules; rabbit; magnetic tracer technique; animal experiment
- From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(11):1360-1364
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the feasibility of using magnetic beads to locate small pulmonary nodules. Methods Twelve rabbits were randomly divided into two groups, 6 in each group. One group underwent thoracotomy after anesthesia and the other group underwent percutaneous puncture under the guidance of X-ray. One and two cylindrical tracer magnets (magnetic beads) with a diameter of 1 mm and a height of 3 mm were injected adjacent to the imaginary pulmonary nodules in left lung in each group. The magnetic beads beside the imaginary nodules were attracted by a pursuit magnet with a diameter of 9 mm and a height of 19 mm. The effectiveness of localization by magnetic beads were determined by attraction between tracer and pursuit magnets. Results All processes were uneven in 12 rabbits. There was micro hemorrhage and no hematoma in the lung tissue at the injection site of the magnetic beads. When tracked with the pursuit magnets, there was one bead divorce in cases that one bead was injected, but no migration or divorce of the magnetic beads in cases that two magnetic beads were simultaneously injected to localize the small pulmonary nodules. Conclusion The feasibility of using magnetic beads to locate small pulmonary nodules has been preliminarily verified.
