The risk factors for recurrence of peripheral solid small-nodule lung cancer (diameter≤ 2 cm) and the impact of different surgery types on survival: A propensity-score matching study
- VernacularTitle:周围型实性小结节肺癌（直径≤2 cm）术后复发转移危险因素分析及手术方式对生存影响的倾向性评分匹配研究
- Author:
Jian ZHOU
1
;
Congjia XIAO
1
;
Qiang PU
1
;
Jiandong MEI
1
;
Lin MA
1
;
Feng LIN
1
;
Chengwu LIU
1
;
Chenglin GUO
1
;
Hu LIAO
1
;
Yunke ZHU
1
;
Quan ZHENG
1
;
Lei CHEN
1
;
Guowei CHE
1
;
Yun WANG
1
;
Yidan LIN
1
;
Yingli KOU
1
;
Yong YUAN
1
;
Yang HU
1
;
Zhu WU
1
;
Lunxu LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Solid small-nodule; recurrence; risk factor; surgery; propensity-score matching study
- From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(11):1283-1291
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the risk factors for postoperative recurrence of peripheral solid small-nodule lung cancer (PSSNLC) (T≤2 cm), and to explore the effects of surgery types on prognosis. Methods We extracted data from Western China Lung Cancer Database (WCLCD), a prospectively maintained database at the Department of Thoracic Surgery, West China Hospital, Sichuan University, and Surveillance, Epidemiology, and End Results (SEER) database for peripheral solid small-nodule lung cancer patients (T≤2 cm N0M0, stageⅠ) who underwent surgery between 2005 and 2016. We used univariable and multivariable logistic regression to analyze risk factors for recurrence of PSSNLC. We applied propensity-score matching to compare the long-term results of segmentectomy and lobectomy, as well as the survival of patients from WCLCD and SEER. We finally included 4 800 patients with PSSNLC (T≤2 cm N0M0)(WCLCD: SEER=354∶4 446). We matched 103 segmentectomies and 350 lobectomies in T≤1 cm, and 280 segmentectomies and 1 067 lobectomies in 1 cm
