The surgical treatment of small cell lung cancer (SCLC) needs re-thinking
- VernacularTitle:小细胞肺癌的外科治疗需要重新审视
- Author:
Keneng CHEN
1
Author Information
- Publication Type:Journal Article
- Keywords: Small cell lung cancer; early stage; surgery
- From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(11):1261-1266
- CountryChina
- Language:Chinese
- Abstract: TNM system should be used in the staging of small cell lung cancer (SCLC), especially in the limited stages of SCLC. Preoperative staging should be strengthened to avoid invalid operation due to insufficient diagnosis. Retrospective studies showed that the efficacy of surgery (+ chemotherapy) in early SCLC is comparable to the outcome of resection for early stage non-small cell lung cancer, which shakes the concept of "chemotherapy/chemoradiotherapy as the main treatment of SCLC". The best operative procedure of SCLC is lobectomy. Sub-lobectomy and pneumonectomy are inferior to that of lobectomy, but still better than chemotherapy/chemo-radiotherapy in terms to long term survival. All these findings need to be confirmed by large sample prospective randomized studies.
