Epidemiological characteristics and drug resistance of Salmonella isolated from diarrhea patients in Jiading District of Shanghai
10.19428/j.cnki.sjpm.2021.20536
- VernacularTitle:上海市嘉定区腹泻患者沙门菌流行病学特征及耐药性分析
- Author:
Wei YU
1
;
Pan SUN
1
;
Pei-chao CHEN
1
;
Xiao-fang GAO
1
Author Information
1. Jiading District Center for Disease Control and Prevention， Shanghai 201899， China
- Publication Type:Research Article
- Keywords:
Salmonella;
epidemiology;
serotype;
drug resistance
- From:
Shanghai Journal of Preventive Medicine
2021;33(10):929-934
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the epidemiological characteristics and drug resistance of Salmonella in patients with food-borne diarrhea in Jiading District. Methods:From January 2018 to December 2019， feces or anal swabs of patients were collected from five hospitals in monitoring sites， and the drug sensitivity test was conducted using the micro broth dilution method. Results:The total detection rate of Salmonella was 7.85% （142/1 810）， and the detection rates of 0-6， 7-17， 18-40， 41-65 and over 65 years old were 8.97% （13/145）， 6.94% （5/72）， 7.58% （75/989）， 8.69% （41/472） and 6.06% （8/132）， respectively. Salmonella rosenbergii was a new dominant serotype in this area. Many strains were resistant to the third and fourth generation cephalosporins， fluoroquinolones and even azithromycin. The sensitivity rate of Salmonella typhimurium to cefotaxime and cefepime was 84.85%， and the resistance rate to fluoroquinolones was 12% to 16%. The mediating rates of Salmonella and Salmonella enteritidis to fluoroquinolones were 56% to 60% and 95.56%， respectively. Conclusion:The detection rate of Salmonella infection is high in all age groups. It is necessary to pay more attention to new dominant serotypes. Salmonella typhimurium is highly resistant to the third and fourth generation cephalosporins and fluoroquinolones， while the sensitivity of Salmonella， especially Salmonella enteritidis to fluoroquinolones has decreased significantly.
