Mechanical Properties of Calcification from Human Aortic Valve

VernacularTitle:人体主动脉瓣膜钙化组织的力学性质
Author: Xianda YANG ¹ ; Wentao FENG ¹ ; Kun LIU ² ; Haibo ZHANG ² ; Jie YAO ¹ ; Chenglong FENG ¹ ; Lizhen WANG ¹ ; Yubo FAN ¹
Author Information

1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Centre for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University
2. Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University
Publication Type:Journal Article
Keywords: aortic valve; leaflets; calcification; nanoindentation; elastic modulus
From: Journal of Medical Biomechanics 2021;36(5):E747-E750
CountryChina
Language:Chinese
Abstract: Objective To measure mechanical properties of calcified tissues from human aortic valve by nanoindentation test. Methods Leaflets from 5 patients with aortic stenosis were collected. Elastic modulus and hardness of the calcified leaflets were obtained by nanoindentationtest. Results The elastic modulus and hardness of the calcified leaflets were (15.69±3.89) GPa and (0.59±0.15) GPa, respectively. Conclusions The elastic modulus and hardness of the calcified valve tissues can be obtained by nanoindentationtest, which provides experimental data for biomechanical research of the valve.