A Case of Angiocentric T-cell Lymphoma of the Esophagus.
- Author:
Sung Kwon BAE
1
;
Eun Sang KUWON
;
Myung Sun JOO
;
Woo CHOI
;
Don Haeng LEE
;
Pum Soo KIM
;
Hyeon Geun CHO
;
Yong Woon SHIN
;
Young Soo KIM
;
Tae Sook HWANG
Author Information
1. Department of Internal Medicine, Inha University, College of Medicine, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Angiocentric T-cell lymphoma;
Esophagus;
Angioinvasive
- MeSH:
Adult;
B-Lymphocytes;
Biopsy;
Deglutition Disorders;
Endoscopy;
Esophagus*;
Follow-Up Studies;
Humans;
Larynx;
Lymphocytes;
Lymphoma;
Lymphoma, T-Cell*;
Male;
Phenotype;
T-Lymphocytes*;
Ulcer;
Weight Loss
- From:Korean Journal of Gastrointestinal Endoscopy
1998;18(4):553-559
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study we present a case of an angiocentric T-cell lymphoma (ACTL) which involve the esophagus. A 37-year-old male was admitted with dysphagia, odynophagia, and weight loss for 3 months. Two months before his admission, he had undergone on endoscopy with a biopsy. The first endoscopic findings revealed a large ulcerative lesion on the esophagus, although there had been no evidence of lymphoma upon microscopic examination. On the follow up endoscopic examination, this ulcerative lesion revealed progressive and destructive change. Histopathology of the third biopsied specimens showed large atypical lymphocyte infiltrates with angiocentric and angioinvasive features. Immunohistochemical studies revealed that the atypical (large) lymphocytes had T-cell phenotypes (CD3+, CD5+, and CD43+) and contained few reactive B-cells (CD20+), We assume that this is the first case of ACTL involving the esophagus and larynx.
