A Case of Primary Gastric Amyloidosis Diagnosed by Endoscopy.
- Author:
Suk Ho LEE
1
;
Poong Lyul RHEE
;
Jae Jun KIM
;
Kyu Taek LEE
;
Joon Hyoek LEE
;
Jong Kyun LEE
;
Hee Jung SON
;
In Koo KANG
;
Sung Yun OH
;
Kwang Cheol KOH
;
Seung Woon PAIK
;
Jong Chul RHEE
;
Kyu Wan CHOI
;
Young Lyun OH
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Sung Kyun Kwan University College of Medicine Samsung Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Primary amyloidosis;
Stomach
- MeSH:
Amyloid;
Amyloidosis*;
Biopsy;
Birefringence;
Congo Red;
Diagnosis;
Endoscopy*;
Extracellular Space;
Hand;
Microscopy;
Mucous Membrane;
Phagocytosis;
Plaque, Amyloid;
Proteolysis;
Stomach
- From:Korean Journal of Gastrointestinal Endoscopy
1998;18(4):561-566
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amyloidosis is characterized by deposition of amyloid, which is resistant to proteolysis & phagocytosis, in intercellular spaces & vascular walls. The amyloid deposition provokes dysfunction of an accumulated organ & displays variable clinical symptoms depending upon the involved organ. A diagnosis is rendered through a biopsy of the affected organ, followed by staining using congo red which reveals an apple greenish refractile birefringence via polarizing microscopy. Using an electro-microscopy specific filaments can be found. Amyloidosis is classified into primary amyloidosis, composed of light chain filaments (AL) and secondary amyloidosis, comprised of A protain (AA). The AL type of amyloidosis shows deposition of amyloid in muscularis mucosa & muscularis externa. Priunary amyloidosis on the other hand, is relatively rare. We experienced primary stornach amyloidosis (AL), which was mistaken for stomch cancer.
