Evaluation of antibacterial activity against Candida albicans according to the dosage of various denture cleansers
10.4047/jap.2021.13.2.100
- Author:
Cha-Hwan BAE
1
;
Yun-Kyong LIM
;
Joong-Ki KOOK
;
Mee-Kyoung SON
;
Yu-Ri HEO
Author Information
1. Department of Prosthodontics, School of Dentistry, Chosun University, Gwangju, Republic of Korea
- Publication Type:Original Articles
- From:The Journal of Advanced Prosthodontics
2021;13(2):100-106
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE:The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans.
Materials and methods:This study used tablet-type denture cleansers, PolidentⓇ , CoolingdentⓇ and FittydentⓇ , along with liquid denture cleansers, HexamedineⓇ , ListerineⓇ and Apple vinegarⓇ . The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers.
Results:In the 0.5 × 106 cfu/㎖ culture medium, the C. albicans’ death rate of PolidentⓇ was significantly lower than those of FittydentⓇ , HexamedineⓇ , ListerineⓇ , and Apple vinegarⓇ (P <.05). In the 0.5 × 107 cfu/, the C. albicans’ death rates of PolidentⓇ and CoolingdentⓇ were significantly lower than those of FittydentⓇ , HexamedineⓇ , ListerineⓇ and Apple vinegarⓇ (P <.05). The C. albicans’ death rates of PolidentⓇ and CoolingdentⓇ were significantly decreased at 0.02 g and 0.01 g. The C. albicans’ death rate of FittydentⓇ was significantly decreased at 0.005 g (P <.05). The C. albicans’ death rate of HexamedineⓇ was significantly decreased at 1/16 dilution. The C. albicans’ death rate of ListerineⓇ was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegarⓇ was decreased at 1/4 dilution (P<.05).
Conclusion:As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans’ death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.
