Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
10.5469euroint.2020.00339
- Author:
Jin Soo LEE
1
;
Yang-Ha HWANG
;
Sung-Il SOHN
Author Information
1. Department of Neurology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea
- Publication Type:Review
- From:Neurointervention
2021;16(2):91-110
- CountryRepublic of Korea
- Language:English
-
Abstract:
Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby raising the question of whether the treatment could be generalized. In addition, there remains a concern on the feasibility of the method with respect to its application against intracranial atherosclerosis (ICAS)-related LVO, frequently observed in the Asian population. It is important to include evidence on ICAS LVO from Asian countries in the future for a comprehensive understanding of LVO etiology. Besides the issues with EVT, prognostic concerns in diabetes patients, acute kidney injury following EVT, neuroprotective management against reperfusion injury, and other peri-EVT issues should be considered in clinical practice. In the current article, we present an in-depth review of the literature that revises information pertaining to such concerns.
