Macasiamenene V, a New Stilbenoid from the Leaves of Macaranga inermis
- Author:
Muhammad Fajar ALDIN
1
;
Tjitjik Srie TJAHJANDARIE
;
Ratih Dewi SAPUTRI
;
Mulyadi TANJUNG
Author Information
- Publication Type:Original Article
- From:Natural Product Sciences 2021;27(1):45-48
- CountryRepublic of Korea
- Language:English
- Abstract: One new compound, macasiamenene V (1), and two known stilbenes (2 - 3) were isolated from Macaranga inermis Pax & K.Hoffm leaves. The structure of 1 was fully assigned based on the information on high-resolution MS and (1D, 2D) NMR spectra. The cytotoxic of compounds 1 - 3 was evaluated against 4T1 and HeLa cells. Compounds 2 - 3 showed high activity against HeLa cells with an IC 50 value of 1.09 and 0.88 μg/mL, respectively.
