Analysis of the Bioactive Metabolites of the Endangered Mexican LostFungi Campanophyllum – A Report from India
10.1080/12298093.2020.1723388
- Author:
Madhusmita BORTHAKUR
1
;
Arun Bahadur GURUNG
;
Atanu BHATTACHARJEE
;
S. R. JOSHI
Author Information
1. Microbiology Laboratory, Department of Biotechnology and Bioinformatics, North-Eastern Hill University, Shillong, India
- Publication Type:RESEARCH ARTICLE
- From:Mycobiology
2020;48(1):58-69
- CountryRepublic of Korea
- Language:English
-
Abstract:
Meghalaya, (in India), in the region of the mega-biodiversity hotspots, is home to a plethoraof wild mushrooms. The present study concerns the exploration of the order Agaricales,which includes rare gilled mushrooms considered endangered under IUCN A4c criteria, dueto the declining habitat. Electron microscopy of the gill sections revealed an abundance ofclamp connections, hyphal cell walls, cystidia, and basidia. This rare species which belongsto the family Cyphellaceae, exhibits morphological and molecular differences from theCyphella spp. Phylogenetic analysis revealed that it formed a clade under the genusCampanophyllum of the order Agaricales, confirmed by both Neighbor Joining (NJ) andBayesian phylogenetic analysis. Being nutritionally potent along with its efficient antioxidantvalue, the fungal extract shows significant rise of two-fold in the antimicrobial activity alongwith the commercial antibiotics. The compound, Phenol, 2, 4-bis (1, 1-Dimethylethyl) (2, 4-DTBP) showed in ample range in the fungal extract along with aliphatic hydrocarbons,terpene, alcohol and volatile organic compounds on further characterization in GCMS. Thepresent study indicates the endangered Campanophyllum proboscideum could be a richsource of natural antioxidants and an effective pharmaceutical agent.
