Comparison of IRIS Iq200, UF-1000i, and Cobas u701 Module Automated Urine Sediment Analyzers
10.47429/lmo.2020.10.4.283
- Author:
Hyunji CHOI
1
;
Dahae YANG
;
Sun Ja KWON
;
Poo Reum KANG
;
Hasung PARK
;
Teayun KIM
;
Hyunyong HWANG
Author Information
1. Department of Laboratory Medicine, Kosin University Gospel Hospital, Busan, Korea
- Publication Type:Original Article
- From:Laboratory Medicine Online
2020;10(4):283-294
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:We sought to compare the performance of three commercially available automated urine sediment analyzers that represent the current urine sediment analysis technology.
Methods:A total of 232 patient samples were analyzed using manual microscopy and three automated analyzers: IRIS Iq200 (Beckman Coulter, USA), UF-1000i (Sysmex, Japan), and Cobas u701 (Roche, Switzerland). We analyzed precision, linearity, carry-over, concordance rate, and agreement between the three analyzers and manual microscopy.
Results:The repeatability and within-laboratory precision showed results similar to those of previous studies. All analyzers showed excellent linearity. The carry-over rates were within 1%. The correlation coefficient (r) between the three analyzers and manual microscopy was good. Regarding red blood cell (RBC), the UF-1000i showed a better concordance rate (90.52%) with manual microscopy than the other two analyzers and the agreement was substantial for UF-1000i (κ=0.63) and IRIS Iq200 (κ=0.61). Regarding white blood cell (WBC), Cobas u701 showed the best concordance rate (96.55%) and the agreement was moderate for IRIS Iq200 (κ=0.57) and Cobas u701 (κ=0.56), and fair for UF-1000i (κ=0.47). Regarding epithelial cell (EPI), IRIS Iq200 showed the highest concordance rate (99.2%) and the agreement was moderate for IRIS Iq200 (κ=0.59) and Cobas u701 (κ=0.54), and fair for UF-1000i (κ=0.40).
Conclusions:IRIS Iq200 offered the best agreement with manual microscopy for WBC and EPI count, while UF-1000i showed a better agreement for RBC count. The agreement is insufficient for fully replacing the manual microscopy.
