Characteristics of Acromegaly in Korea with a Literature Review.
10.3803/EnM.2013.28.3.164
- Author:
Jae Won HONG
1
;
Cheol Ryong KU
;
Sun Ho KIM
;
Eun Jig LEE
Author Information
1. Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ejlee423@yuhs.ac
- Publication Type:Review
- Keywords:
Acromegaly;
Growth hormone;
Pituitary neoplasms
- MeSH:
Acromegaly;
Growth Hormone;
Humans;
Incidence;
Korea;
Pituitary Neoplasms;
Treatment Outcome
- From:Endocrinology and Metabolism
2013;28(3):164-168
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acromegaly is a slowly progressive disease caused by excessive growth hormone (GH), which is related to a GH secreting pituitary tumor in most cases. Herein, we describe the epidemiology, clinical characteristics, and treatment of acromegaly in Korea with a literature review. The average annual incidence of acromegaly in Korea was 3.9 cases per million people, which was within the range of previous Western studies. The primary treatment for acromegaly was also transsphenoidal adenomectomy, which accounted for 90.4% of patients whose primary therapeutic options were known. The overall surgical remission rates were 89%, 87%, 64%, 70%, and 50% for modified Hardy classification I, II, IIIA, IIIB, and IV, respectively. An updated and larger study regarding the treatment outcome of medical/radiotherapy in Korean acromegalic patients is needed.
