Long-Term Outcomes of Trabeculectomy in Korean Patients with Juvenile Open-Angle Glaucoma.
10.3341/jkos.2014.55.2.252
- Author:
Eun Kyu OH
1
;
Eun Ji LEE
;
Jin Wook JEOUNG
;
Seok Hwan KIM
;
Tae Woo KIM
;
Ki Ho PARK
;
Dong Myoung KIM
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. opticdisc@gmail.com
- Publication Type:Original Article
- Keywords:
Juvenile open-angle glaucoma;
Prognostic factor;
Surgical outcomes;
Trabeculectomy
- MeSH:
Blister;
Follow-Up Studies;
Glaucoma, Open-Angle*;
Humans;
Intraocular Pressure;
Mitomycin;
Postoperative Complications;
Proportional Hazards Models;
Retrospective Studies;
Trabeculectomy*
- From:Journal of the Korean Ophthalmological Society
2014;55(2):252-260
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the outcomes and prognostic factors of trabeculectomy with mitomycin C in Korean patients with juvenile open-angle glaucoma (JOAG). METHODS: A retrospective review was performed on 29 eyes with JOAG who had undergone trabeculectomy between January 2004 and January 2013. Intraocular pressure (IOP) and postoperative complications were monitored at 1 day preoperatively, at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively, and at final follow-up after postoperative 18 months. Surgical success was defined as a final IOP of <21 mm Hg or <80% of preoperative IOP, regardless of the use of anti-glaucoma medication. Prognostic factors for surgical success or failure were analyzed by the Cox proportional hazards model. RESULTS: Mean (+/- standard deviation) age at trabeculectomy was 24.6 (+/- 8.9) years, and mean follow-up period was 24.3 (+/- 20.8) months. The overall success rate was 82.8% at final follow-up. The Kaplan-Meier cumulative probabilities of surgical success were 100% at 1 year, 87.4% at 2 years, and 78.7% at 3 years postoperatively. The Cox proportional hazards model failed to determine any significant factors that were associated with surgical failure. The three most frequent postoperative complications were immediately postoperative hypotony (n = 19, 65.5%), hypotony maculopathy (n = 8, 27.6%), and encapsulated bleb (n = 8, 27.6%), most of which were resolved after a minor procedure or observation. Two of 8 eyes with encapsulated bleb required a second surgery. There were no vision-threatening severe complications. CONCLUSIONS: Trabeculectomy with MMC may be an effective treatment in Korean JOAG patients.
