Systemic Lupus Erythematosus Manifested as Pancytopenia during Tuberculosis Treatment
10.3904/kjm.2021.96.2.147
- Author:
Won BAE
1
;
Jieun KANG
;
So-Hee PARK
;
Hyung Koo KANG
;
Hyeon-Kyoung KOO
;
Hye Kyeong PARK
;
Sung-Soon LEE
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea
- Publication Type:Case Report
- From:Korean Journal of Medicine
2021;96(2):147-151
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 49-year-old Chinese woman presented to Ilsan Paik Hospital emergency department with fever and general weakness. Chest computed tomography revealed cavity and peribronchial nodules and consolidation in the right upper lobe. A diagnosis of suspected active tuberculosis was made. A review of the patient’s medication prescribed at another hospital indicated that she had been taking antituberculosis medication for several months. Initially, the patient had anemia and mild thrombocytopenia. In addition, she developed leukopenia and her thrombocytopenia worsened. After discontinuing the antituberculosis medication, her pancytopenia initially improved, but was aggravated again after starting on antituberculosis drugs. Despite discontinuing the antituberculosis medication again, her pancytopenia progressed. As she had a high anti-nuclear antibody titer, another systemic disease was suspected. She was diagnosed with systemic lupus erythematosus and her leukopenia and thrombocytopenia improved after initiation of treatment with systemic steroids and antimalarial drugs
