Development of Systemic Lupus Erythematosus after Total Resection of a Thymoma for Myasthenia Gravis.
- Author:
Mi Seung SHIN
1
;
Jin Wha LEE
;
Tae Rim SHIN
;
Ka Eun WOO
;
Hyun Kyung LEE
;
Young Sun KIM
;
Young Joo CHO
Author Information
1. Department of Internal Medicine, Ewha Womans University, college of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Myas thenia gravis
- MeSH:
Diagnosis, Differential;
Exanthema;
Fatigue;
Female;
Fever;
Humans;
Immunologic Factors;
Leukopenia;
Lupus Erythematosus, Systemic*;
Mya;
Myasthenia Gravis*;
Thymectomy;
Thymoma*;
Young Adult
- From:Korean Journal of Medicine
1998;54(3):451-455
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus and myasthenia gravis are autoimmune disorders in which genetic, environmental and hormonal as well as immunological factors have been implicated. We experienced a case of 24 year-old female patient developed SLE(anemia, leukopenia, facial malar rash, high titers of anti-DNA and anti-nuclear antibody) 3 years following successful therapeutic thymectomy for myas thenia gravis. A review of the world-wide literature revealed 8.3% to 24.3% association between myasthenia gravis and SLE. However there has been no controlled epidemiological study to prove a real association between these two disease. The differential diagnosis of fatigue and fever in patient with SLE should always include the possibility of myasthenia gravis.
