Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
- Author:
Sung Jae KIM
1
;
Cheongung KIM
;
Hee Chun CHUNG
;
Yong Ho PARK
;
Kun Taek PARK
Author Information
- Publication Type:Rapid Communication
- From:Journal of Veterinary Science 2021;22(3):e32-
- CountryRepublic of Korea
- Language:English
- Abstract: Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.
